It shares epidemiological and pathological features with, but is less common than its pleural counterpart, which is described in detail in the general article on mesothelioma. Other sub-types (also discussed separately) include :
* multicystic mesothelioma
* pericardial mesothelioma
Epidemiology
Approximately 20 - 30% of mesotheliomas arise from the peritoneal serosal lining. As with pleural mesothelioma, there is also a strong association with asbestos exposure, and this occupational hazard probably accounts for disease predominance in middle aged to older males. Despite this, approximately 50% of cases have no history of exposure to asbestos.
Overall incidence is at approximately 1 - 2 cases/million.
Clinical presentation
Typically patients present with weight loss, abdominal pain and/or abdominal distension.
There is a reported correlation between the clinical presentation and CT findings, with subgrouping into 2:
* “dry-painful” type : presenting with abdominal pain, CT features of peritoneal mass(es) and little to no ascites;
* “wet” type : presenting with abdominal distension, CT findings of ascites and widespread nodules without a predominant mass and
* mixed type with both pain and ascites present
Pathology
As with pleural mesothelioma, three histologic sub-types exist :
* epithelial
* sarcomatoid and
* biphasic (mixed epithelial-sarcomatoid)
* multicystic mesothelioma
* pericardial mesothelioma
Epidemiology
Approximately 20 - 30% of mesotheliomas arise from the peritoneal serosal lining. As with pleural mesothelioma, there is also a strong association with asbestos exposure, and this occupational hazard probably accounts for disease predominance in middle aged to older males. Despite this, approximately 50% of cases have no history of exposure to asbestos.
Overall incidence is at approximately 1 - 2 cases/million.
Clinical presentation
Typically patients present with weight loss, abdominal pain and/or abdominal distension.
There is a reported correlation between the clinical presentation and CT findings, with subgrouping into 2:
* “dry-painful” type : presenting with abdominal pain, CT features of peritoneal mass(es) and little to no ascites;
* “wet” type : presenting with abdominal distension, CT findings of ascites and widespread nodules without a predominant mass and
* mixed type with both pain and ascites present
Pathology
As with pleural mesothelioma, three histologic sub-types exist :
* epithelial
* sarcomatoid and
* biphasic (mixed epithelial-sarcomatoid)
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