Malignant mesotheliomas have assumed an importance in the medical and lay literature out of proportion to their incidence in the American population, chiefly due to the known association of pleural mesothelioma with asbestos exposure. Data from the Connecticut tumor registry suggest that this tumor is increasing in incidence. Based on exposures between 1940 and approximately 1970, when industrial precautions were first instituted, epidemiologists estimate that the number of new cases of mesothelioma will peak sometime in the 1990s and that mesothelioma will thereafter become less common.
These models generally assume that asbestos exposures after 1970 will be insignificant. While industrial levels that are legal today will almost certainly prevent the development of severe asbestosis in most workers, unfortunately a threshold of exposure below which there is no risk of mesothelioma has not been documented.
Asbestos continues to be used in floor and ceiling tiles, in automobile brake linings, and in a variety of other products. At the present time, construction workers who maintain or remove asbestos constitute one of a number of groups with continued exposure.
The diagnosis of a malignant pleural mesothelioma is not difficult provided that the physicians caring for such a patient consider mesothelioma in the differential diagnosis. Patients present with chest pain or shortness of breath, or both, and the initial chest x-ray film most often reveals a large unilateral pleural effusion.
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