Treatment options for the treatment of Mesotheliomas are often determined by the stage of the progression that a Mesothelioma patient is in. Currently, there are three staging systems in use for Pleural Mesothelioma. Each one of these systems measures somewhat different variables. Peritoneal Mesothelioma is not staged.
The Butchart System is the oldest staging system and is the one most often used. The Butchart System is based mainly on the extent of the primary tumor mass and divides Mesotheliomas into four stages. The TNM system is more recent and considers variables of tumor in mass and spread; lymph node involvement; and metastasis. The third system for determining the stage of the Mesothelioma is the Brigham System. This system is the latest and stages the Mesothelioma according to resectability (the ability to surgically remove) and lymph node involvement.
Stage I: The Mesothelioma involves the right or left pleura and may also have spread to the lung, pericardium, or diaphragm on the same side. Lymph nodes are not involved.
* Stage II: The Mesothelioma has spread from the pleura on one side to nearby lymph nodes next to the lung on the same side. It may also have spread into the lung, pericardium, or diaphragm on the same side.
* Stage III: The Mesothelioma has moved into the chest wall, muscle, ribs, heart, esophagus, or other organs in the chest on the same side with or without spread to lymph nodes on the same side as the primary tumor.
* Stage IV: The Mesothelioma has spread into the lymph nodes in the chest on the side opposite the primary tumor, or extends to the pleura or lung on the opposite side, or directly extends into organs in the abdominal cavity or neck. Any distant metastases is included in this stage.
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