Sarcomatoid Mesothelioma
Mesothelioma is a rare, lethal form of cancer affecting the thin layer of tissue surrounding many internal organs. Pleural mesothelioma, which affects the lining surrounding the lungs, represents approximately 90% of mesothelioma cases. Accordingly, exposure to airborne asbestos fibers is the primary risk factor for developing mesothelioma and asbestos exposure increases mesothelioma risk by 10 to 20%. The next most common form of mesothelioma is peritoneal mesothelioma, which affects the layer of tissue surrounding abdominal organs.
Prognosis and Life Expectancy
Unfortunately, mesothelioma is almost always diagnosed after it spreads and the prognosis is generally poor. The overall survival expectancy for patients is between 8 and 14 months, even with treatment.
cancer cellTypes of Mesothelioma
The most lethal type of mesothelioma, in terms of life expectancy, is sarcomatoid. This type occurs in about 10 to 20% of mesothelioma patients. The other main types of mesothelioma are epithelial and biphasic, which affect 50 to 70% and 20 to 35% of patients, respectively. Biphasic mesothelioma consists of cells with both epithelioid and sarcomatoid histological features. Classifying mesothelioma tumors by type is diagnostically useful and predictive of survival rates. For example, epithelioid tumors respond better to treatment as evidenced by longer patient survival rates and mixed tumors tend to have an intermediate response to treatment.
Mesothelioma is a rare, lethal form of cancer affecting the thin layer of tissue surrounding many internal organs. Pleural mesothelioma, which affects the lining surrounding the lungs, represents approximately 90% of mesothelioma cases. Accordingly, exposure to airborne asbestos fibers is the primary risk factor for developing mesothelioma and asbestos exposure increases mesothelioma risk by 10 to 20%. The next most common form of mesothelioma is peritoneal mesothelioma, which affects the layer of tissue surrounding abdominal organs.
Prognosis and Life Expectancy
Unfortunately, mesothelioma is almost always diagnosed after it spreads and the prognosis is generally poor. The overall survival expectancy for patients is between 8 and 14 months, even with treatment.
cancer cellTypes of Mesothelioma
The most lethal type of mesothelioma, in terms of life expectancy, is sarcomatoid. This type occurs in about 10 to 20% of mesothelioma patients. The other main types of mesothelioma are epithelial and biphasic, which affect 50 to 70% and 20 to 35% of patients, respectively. Biphasic mesothelioma consists of cells with both epithelioid and sarcomatoid histological features. Classifying mesothelioma tumors by type is diagnostically useful and predictive of survival rates. For example, epithelioid tumors respond better to treatment as evidenced by longer patient survival rates and mixed tumors tend to have an intermediate response to treatment.
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