Alessio Bridda, MD, Third-year Resident in General Surgery, Ilaria Padoan, MD, Third-year Resident in Pathology, Roberto Mencarelli, MD, Staff Physician, and Mauro Frego, MD, Assistant Professor of Surgery
Alessio Bridda, Clinica Chirurgica I, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy;
Contributor Information.
Disclosure: Alessio Bridda, MD, has disclosed no relevant financial relationships.
Disclosure: Ilaria Padoan, MD, has disclosed no relevant financial relationships.
Disclosure: Roberto Mencarelli, MD, has disclosed no relevant financial relationships.
Disclosure: Mauro Frego, MD has disclosed no relevant financial relationships.
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Abstract
Background
Malignant peritoneal mesothelioma (MPM) is a rare aggressive tumor of the peritoneum, regarded as a universally fatal disease. It is poorly described and the knowledge of its natural history is very limited. Occupational and environmental asbestos exposure still remains a public health problem around the world. The incidence has increased in the past 2 decades. Only 20% to 33% of all mesotheliomas arise from the peritoneum itself; the pleura is the most common site of origin.
o References
Epidemiology
Mesotheliomas are aggressive tumors arising from serous surfaces: pleura (65%-70%), peritoneum (30%), tunica vaginalis testis, and pericardium (1%-2%).[1] Peritoneal mesothelioma was first described in 1908 by Miller and Wynn. It is a rare neoplasm with a rapid fatal course (median survival 6-12 months,[2] mean symptoms-to-survival time 345 days[3]). In the United States, the overall prevalence is 1-2 cases per million, with an estimated incidence of 200-400 new cases annually. It was exceedingly rare until 1930, when industry increased the use of asbestos, which is the principal risk factor for the disease. It can occur in any age group, although the 50- to 69-year age group is the most affected[4,5]: only an estimated 2% to 5% of all cases mesothelioma present in the first 2 decades of life.[6] It is more common in men, possibly because of the higher male occupational exposure to asbestos.[7]
Alessio Bridda, Clinica Chirurgica I, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Via Giustiniani 2, Policlinico III Piano, 35128 Padova, Italy;
Contributor Information.
Disclosure: Alessio Bridda, MD, has disclosed no relevant financial relationships.
Disclosure: Ilaria Padoan, MD, has disclosed no relevant financial relationships.
Disclosure: Roberto Mencarelli, MD, has disclosed no relevant financial relationships.
Disclosure: Mauro Frego, MD has disclosed no relevant financial relationships.
Small right arrow pointing to: This article has been cited by other articles in PMC.
Abstract
Background
Malignant peritoneal mesothelioma (MPM) is a rare aggressive tumor of the peritoneum, regarded as a universally fatal disease. It is poorly described and the knowledge of its natural history is very limited. Occupational and environmental asbestos exposure still remains a public health problem around the world. The incidence has increased in the past 2 decades. Only 20% to 33% of all mesotheliomas arise from the peritoneum itself; the pleura is the most common site of origin.
o References
Epidemiology
Mesotheliomas are aggressive tumors arising from serous surfaces: pleura (65%-70%), peritoneum (30%), tunica vaginalis testis, and pericardium (1%-2%).[1] Peritoneal mesothelioma was first described in 1908 by Miller and Wynn. It is a rare neoplasm with a rapid fatal course (median survival 6-12 months,[2] mean symptoms-to-survival time 345 days[3]). In the United States, the overall prevalence is 1-2 cases per million, with an estimated incidence of 200-400 new cases annually. It was exceedingly rare until 1930, when industry increased the use of asbestos, which is the principal risk factor for the disease. It can occur in any age group, although the 50- to 69-year age group is the most affected[4,5]: only an estimated 2% to 5% of all cases mesothelioma present in the first 2 decades of life.[6] It is more common in men, possibly because of the higher male occupational exposure to asbestos.[7]
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