Impact of Asbestos Fibers on the PeritoneumOne of the most common symptoms of peritoneal mesothelioma is ascites, or the accumulation of excess fluid in the abdominal cavity. This symptom can be assigned to a number of more common conditions, from liver disease to intestinal problems. Just as with pleural mesothelioma, the nature of the symptoms can be misleading.
One study cited a mean period of 122 days from the presentation of symptoms to diagnosis.
Once in the peritoneum, asbestos fibers cause changes in peritoneal cells that cause them to divide without restraint, causing the peritoneal layers to thicken. The growth of cancer cells puts pressure on internal organs, and this pressure is increased by the fluid buildup. The accumulation of pressure can mesothelioma sometimes cause adjacent organs to begin to malfunction, further complicating diagnosis. Intestinal obstruction can occur, as can emergency surgery due to inflammatory lesions. Thrombosis in the veins and hypoglycemia are common symptoms.
Despite the evidence of some sort of highly intrusive affliction, CT scans and radiology exams won't result in a firm diagnosis. A precise diagnosis based on imaging alone is not possible. Peritoneal mesothelioma may consist of a single tumor, diffuse mesothelioma small tumors, or a combination along with benign calcified nodules. It is not a disease that can easily be addressed surgically
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